What AOD-9604 is
AOD-9604 is a synthetic peptide corresponding to a modified fragment of the C-terminal region of human growth hormone (residues 177-191), with an additional N-terminal tyrosine residue for chemical stability. It was originally investigated as part of a research programme exploring fat-metabolism activity attributed to the C-terminal region of hGH.
Molecular information
- Sequence-origin: Modified hGH(177-191) fragment (Tyr-hGH(177-191))
- Number of residues: 16
- Approximate monoisotopic mass: ~1815 Da (as the free acid)
- Physical form: Typically supplied as a white lyophilised powder
Areas of published research
Preclinical research has examined AOD-9604 in the context of adipocyte biology and lipid metabolism. Published human clinical data are limited to earlier pharmaceutical development studies. As a modest-sized peptide, AOD-9604 is amenable to standard reversed-phase HPLC with UV detection at 214 nm and LC-MS for identity confirmation.
Analytical considerations
Standard research-peptide analytical checks apply: identity confirmation by mass spectrometry (see LC-MS peptide testing explained), purity assessment by reversed-phase HPLC at 214 nm (see what is HPLC peptide testing), and batch-specific documentation (see how to read a peptide COA). Refer to the Peptovia Research Certificate of Analysis page for live examples of the analytical format used for batches supplied.
Further reading
Peer-reviewed literature on AOD-9604 is accessible via PubMed and specialist journals. Readers are encouraged to evaluate primary sources directly rather than relying on secondary summaries.
Research Use Only. This profile is an educational overview of AOD-9604 as a research peptide. It does not describe or recommend human, veterinary or clinical use. Peptovia Research supplies AOD-9604 strictly for in-vitro laboratory research. No dosing, administration or therapeutic guidance is provided or implied.