What Epithalon is
Epithalon (also spelled Epitalon) is a chemically synthesised tetrapeptide, developed from a Russian research programme investigating the biological activity of short peptides derived from pineal-gland extracts. Its research context centres on gerontology and cellular ageing.
Molecular information
- Sequence: Ala-Glu-Asp-Gly (AEDG)
- Number of residues: 4
- Approximate monoisotopic mass: ~390 Da (as the free acid)
- Physical form: Typically supplied as a white lyophilised powder
Areas of published research
Published research has examined Epithalon's influence on telomerase activity in cell culture, on ageing-related biomarkers in animal models and, in Russian-language clinical literature, on age-related parameters in human studies. As a very short peptide, Epithalon is chromatographically challenging on standard reversed-phase columns; specialist method conditions may be required.
Analytical considerations
Standard research-peptide analytical checks apply: identity confirmation by mass spectrometry (see LC-MS peptide testing explained), purity assessment by reversed-phase HPLC at 214 nm (see what is HPLC peptide testing), and batch-specific documentation (see how to read a peptide COA). Refer to the Peptovia Research Certificate of Analysis page for live examples of the analytical format used for batches supplied.
Further reading
Peer-reviewed literature on Epithalon is accessible via PubMed and specialist journals. Readers are encouraged to evaluate primary sources directly rather than relying on secondary summaries.
Research Use Only. This profile is an educational overview of Epithalon as a research peptide. It does not describe or recommend human, veterinary or clinical use. Peptovia Research supplies Epithalon strictly for in-vitro laboratory research. No dosing, administration or therapeutic guidance is provided or implied.