What GHRP-2 is
GHRP-2 (Growth Hormone-Releasing Peptide 2, also called pralmorelin) is a synthetic hexapeptide developed as a ghrelin-receptor (GHSR-1a) agonist. It was one of the earlier synthetic growth-hormone secretagogues to be studied in growth-hormone-axis research.
Molecular information
- Sequence: D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH₂ (contains non-natural residues)
- Number of residues: 6
- Approximate monoisotopic mass: ~817 Da (as the free acid)
- Physical form: Typically supplied as a white lyophilised powder
Areas of published research
Preclinical and clinical research has examined GHRP-2's effect on GH secretion, appetite signalling and related endocrinological endpoints. Its ghrelin-receptor agonism is well characterised. Non-natural amino acids (D-Nal, D-Phe) in the sequence should be considered when interpreting mass-spectrometry results, since a synthesis error at these positions may not be obvious from mass alone.
Analytical considerations
Standard research-peptide analytical checks apply: identity confirmation by mass spectrometry (see LC-MS peptide testing explained), purity assessment by reversed-phase HPLC at 214 nm (see what is HPLC peptide testing), and batch-specific documentation (see how to read a peptide COA). Refer to the Peptovia Research Certificate of Analysis page for live examples of the analytical format used for batches supplied.
Further reading
Peer-reviewed literature on GHRP-2 is accessible via PubMed and specialist journals. Readers are encouraged to evaluate primary sources directly rather than relying on secondary summaries.
Research Use Only. This profile is an educational overview of GHRP-2 as a research peptide. It does not describe or recommend human, veterinary or clinical use. Peptovia Research supplies GHRP-2 strictly for in-vitro laboratory research. No dosing, administration or therapeutic guidance is provided or implied.