What Ipamorelin is
Ipamorelin is a synthetic pentapeptide growth-hormone secretagogue, developed as a selective ghrelin-receptor (GHSR-1a) agonist. It is often studied and supplied alongside CJC-1295 as part of research on growth-hormone-axis modulation.
Molecular information
- Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (Aib = α-aminoisobutyric acid)
- Number of residues: 5
- Approximate monoisotopic mass: ~711 Da (as the free acid)
- Physical form: Typically supplied as a white lyophilised powder
Areas of published research
Preclinical research on Ipamorelin has examined ghrelin-receptor selectivity, growth-hormone-release profiles and downstream endocrine effects. Its selectivity for the ghrelin receptor over other pituitary-active receptors is a distinguishing feature relative to earlier compounds such as GHRP-2 and GHRP-6. The presence of non-natural residues (Aib, D-Nal, D-Phe) is analytically significant.
Analytical considerations
Standard research-peptide analytical checks apply: identity confirmation by mass spectrometry (see LC-MS peptide testing explained), purity assessment by reversed-phase HPLC at 214 nm (see what is HPLC peptide testing), and batch-specific documentation (see how to read a peptide COA). Refer to the Peptovia Research Certificate of Analysis page for live examples of the analytical format used for batches supplied.
Further reading
Peer-reviewed literature on Ipamorelin is accessible via PubMed and specialist journals. Readers are encouraged to evaluate primary sources directly rather than relying on secondary summaries.
Research Use Only. This profile is an educational overview of Ipamorelin as a research peptide. It does not describe or recommend human, veterinary or clinical use. Peptovia Research supplies Ipamorelin strictly for in-vitro laboratory research. No dosing, administration or therapeutic guidance is provided or implied.