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NAD+: Research Profile

Nicotinamide adenine dinucleotide, a coenzyme central to cellular metabolism and redox biology, supplied as a research reagent for in-vitro laboratory work.

4 min read·10 September 2026

What NAD+ is

NAD+ (nicotinamide adenine dinucleotide, oxidised form) is a coenzyme, not a peptide. It is included here because it is commonly supplied alongside research peptides in a laboratory-supply context. NAD+ is central to cellular redox biology and is a substrate for sirtuins, PARPs and CD38.

Molecular information

  • Compound class: Dinucleotide coenzyme
  • Molecular formula: C₂₁H₂₇N₇O₁₄P₂
  • Approximate molecular mass: ~663 g/mol
  • Physical form: Typically supplied as a white powder

Areas of published research

Published research on NAD+ spans redox biology, cellular energetics, sirtuin activity, DNA-damage response and ageing research. Because NAD+ is a small molecule rather than a peptide, its analytical characterisation uses standard organic-chemistry techniques — HPLC with UV detection at 260 nm (adenine absorbance), LC-MS with electrospray, and enzymatic assays for functional integrity — rather than peptide-specific methods.

Analytical considerations

Standard research-peptide analytical checks apply: identity confirmation by mass spectrometry (see LC-MS peptide testing explained), purity assessment by reversed-phase HPLC at 214 nm (see what is HPLC peptide testing), and batch-specific documentation (see how to read a peptide COA). Refer to the Peptovia Research Certificate of Analysis page for live examples of the analytical format used for batches supplied.

Further reading

Peer-reviewed literature on NAD+ is accessible via PubMed and specialist journals. Readers are encouraged to evaluate primary sources directly rather than relying on secondary summaries.


Research Use Only. This profile is an educational overview of NAD+ as a research peptide. It does not describe or recommend human, veterinary or clinical use. Peptovia Research supplies NAD+ strictly for in-vitro laboratory research. No dosing, administration or therapeutic guidance is provided or implied.